The Buffalo Bills, riding high after a Week 4 victory over the New Orleans Saints, are now facing a potential crisis as their injury report swells with the addition of three rookies ahead of their Week 5 Sunday Night Football clash against the New England Patriots. The latest updates from Orchard Park reveal a troubling situation for the team, with second-round defensive tackle TJ Sanders, fifth-round tight end Jackson Hawes, and sixth-round cornerback Dorian Strong all listed on the injury report, raising concerns about the team’s depth and readiness.

Rookie Woes Threaten Bills’ Momentum
The Bills’ injury report, released on Thursday, October 2, 2025, now includes eight players, with the trio of rookies—Sanders, Hawes, and Strong—joining the list in a matter of days. This development casts a shadow over what has been a promising start to the season for Buffalo, who have leaned on their young talent to complement a veteran-heavy roster.
Dorian Strong (Neck, Did Not Participate): The sixth-round cornerback, who played a role in the Week 4 win, was a non-participant in Thursday’s practice due to a neck injury. His absence from the field adds uncertainty to the Bills’ secondary, which is already navigating challenges.
TJ Sanders (Knee, Limited): The second-round defensive tackle, a key piece of Buffalo’s defensive line rotation, is dealing with a knee injury that limited his participation in practice. Sanders’ injury exacerbates existing depth concerns along the interior defensive line, especially with veteran Ed Oliver still recovering from an ankle injury sustained in Week 2 and rookie DeWayne Carter out for the season.
Jackson Hawes (Ankle, Limited): The fifth-round tight end, who logged 31 offensive snaps in the Week 4 victory, has been limited for two consecutive days due to an ankle issue. It remains unclear whether the injury occurred during Wednesday’s practice or in the September 28 win over the Saints.
All three rookies contributed to Buffalo’s recent success, making their potential absence a significant blow as the team prepares to host the Patriots in a high-stakes primetime matchup.
Defensive Line Depth in Jeopardy
The injury to TJ Sanders is particularly concerning for a Bills defensive line already stretched thin. With only four defensive tackles on the 53-man roster, Buffalo has been operating shorthanded since Ed Oliver’s Week 2 ankle injury. The season-ending injury to DeWayne Carter has forced the team to rely on practice squad elevations to fill gaps on gamedays. Sanders’ limited status further complicates matters, as the rookie has been a critical part of the rotation.
However, there is a glimmer of hope for the Bills’ defensive front. Ed Oliver, a cornerstone of the defensive line, practiced on a limited basis for the second straight day on Thursday. Speaking to reporters on Wednesday, Oliver remained cautiously optimistic about his recovery, stating, “Just day to day. We’re taking steps in the right direction.” His potential return could provide a much-needed boost, but his status for Sunday’s game remains uncertain.
Additional Injury Concerns
Beyond the rookie trio, the Bills are grappling with injuries to other key players. Starting linebacker Matt Milano, sidelined since Week 3 with a pectoral injury, returned to practice on Wednesday and was a limited participant on Thursday. Franchise right tackle Spencer Brown, who tweaked his calf in a September 18 loss to the Miami Dolphins, was also limited in practice. Both players missed the Week 4 win, and their ongoing recovery adds to the uncertainty surrounding Buffalo’s lineup.
Linebacker Dorian Williams, another new addition to the injury report, did not practice for the second consecutive day due to a knee issue. His absence, combined with Strong’s non-participation, could leave the Bills vulnerable on defense.
On a positive note, defensive end Joey Bosa, who was given a veteran rest day on Wednesday, returned to full participation on Thursday, providing some stability to the defensive front.
Bills’ Injury Report (Week 5, as of Thursday, October 2, 2025)
Did Not Participate:
CB Dorian Strong (neck)
LB Dorian Williams (knee)
Limited Participation:
RT Spencer Brown (calf)
LB Matt Milano (pectoral)
DT Ed Oliver (ankle)
TE Jackson Hawes (ankle)
DT TJ Sanders (knee)
Full Participation:
DE Joey Bosa (veteran rest)
What’s at Stake?
The Bills’ promising season, built on a blend of veteran leadership and emerging young talent, now faces an immediate threat. The potential absence of Sanders, Hawes, and Strong could disrupt the team’s rhythm, particularly on defense, where depth is already a concern. With a critical primetime matchup against the New England Patriots looming, Buffalo’s ability to navigate this injury crisis will be pivotal.
The return of key veterans like Oliver, Milano, and Brown could help mitigate the impact, but their limited status leaves their availability in question. As the Bills prepare for Sunday Night Football, all eyes will be on Orchard Park to see how the team adapts to this sudden challenge and whether their depth can hold up against a divisional rival.