The Dallas Cowboys are facing a significant setback as they prepare to take on the Philadelphia Eagles in the 2025-26 NFL season opener at Lincoln Financial Field. The team’s latest injury report, released following Tuesday’s practice, has confirmed a major blow to their defensive line: standout defensive tackle Perrion Winfrey has been officially ruled out for the Week 1 primetime showdown due to a lingering back injury.
Winfrey, who emerged as a preseason standout and was expected to bolster the Cowboys’ defensive front, did not participate (DNP) in practice on both Monday and Tuesday, signaling that his recovery is not progressing as hoped. His absence leaves a glaring hole in Dallas’ defensive strategy against a formidable Eagles offense, which is favored by 8.5 points in Thursday night’s NFC East clash.
While Winfrey’s absence is a major concern, the Cowboys received more positive news regarding other key players. All-Pro cornerback Trevon Diggs (knee), starting left tackle Tyler Guyton (knee), and backup tight end Brevyn Spann-Ford (ankle) were all listed as full participants in Tuesday’s practice. Team sources indicate that these players are “trending in the right direction” to suit up for the game, providing some relief to a Cowboys squad looking to start the season strong.
Dallas Cowboys vs. Philadelphia Eagles: Week 1 Injury Report (Tuesday)
|
Player |
Position |
Injury |
Monday Participation |
Tuesday Participation |
|---|---|---|---|---|
|
Perrion Winfrey |
DT |
Back |
DNP |
DNP |
|
Trevon Diggs |
CB |
Knee |
Full |
Full |
|
Tyler Guyton |
OT |
Knee |
Full |
Full |
|
Brevyn Spann-Ford |
TE |
Ankle |
Full |
Full |
The loss of Winfrey could force the Cowboys to lean heavily on their depth along the defensive line, potentially exposing vulnerabilities against Philadelphia’s potent rushing attack. With the Eagles boasting a high-powered offense and a home-field advantage, Dallas will need to adjust quickly to compensate for their missing star.
Kickoff is scheduled for 8:20 p.m. ET on Thursday, with the game streaming live on Peacock. The over/under for the matchup is set at 47.5 points, and with the Cowboys listed as underdogs, the pressure is on for Dallas to overcome this early adversity.
As the Cowboys prepare for this critical NFC East battle, all eyes will be on how they adapt without Winfrey anchoring the defensive line. Get your popcorn ready—this one’s shaping up to be a thriller.